| 1. | - | | Megan Goethals | 4:43.05a | MI | Michigan Unattached | Midwest Meet of Champions | Sat, Jun 12 |
| 2. | 10 | | Ajee Wilson | 4:43.92a | NJ | Neptune | NJSIAA Groups I, III, & Non-Public A Championships | Sat, May 29 |
| 3. | 9 | | Hannah Meier | 4:45.00 | MI | Grosse Pointe South | MHSAA Regional 10-1 at Grosse Pointe South | Fri, May 21 |
| 4. | 11 | | Alli Billmeyer | 4:45.06a | CA | Torrey Pines | San Diego CIF Finals | Sat, May 29 |
| 5. | 11 | | Chelsey Sveinsson | 4:45.24a | TX | Greenhill | Jesuit-Sheaner Relays | Sat, Mar 27 |
| 6. | 9 | | Claudia Disomma | 4:45.57a | NJ | Sparta | NJSIAA Groups I, III, & Non-Public A Championships | Sat, May 29 |
| 7. | - | | Sara Kroll | 4:46.45a | MI | Michigan Unattached | Midwest Meet of Champions | Sat, Jun 12 |
| 8. | 12 | | Chloe Curtis | 4:46.63a | CA | Redondo Union | California State Meet CIF- Day 2 | Sat, Jun 5 |
| 9. | 12 | | Madeline Chambers | 4:47.23a | OH | Magnificat | OHSAA Division I Track Championships - Region 2 - Amherst | Fri, May 28 |
| 10. | 12 | | Megan Goethals | 4:47.37a | MI | Rochester | MHSAA D1 Track and Field Championships | Sat, Jun 5 |
| 11. | 12 | | Arianna Vailas | 4:47.48a | NH | Manchester Central | New England Championship | Sat, Jun 12 |
| 12. | 11 | | Lindsay Crevoiserat | 4:47.75a | CT | Glastonbury | New England Championship | Sat, Jun 12 |
| 13. | 12 | | Marielle Hall | 4:48.73a | NJ | Haddonfield Memorial | NJSIAA Groups II, IV, & Non-Public B Championships | Sat, May 29 |
| 14. | 12 | | Kathleen Stevens | 4:49.39a | VA | Blacksburg | VHSL Region IV Championships | Fri, May 28 |
| 15. | 12 | | Anna Dailey | 4:49.41a | WA | Garfield | 4A Kingco Championship Meet | Wed, May 12 |
| 16. | 12 | | Joanna Stevens | 4:49.50a | VA | Blacksburg | VHSL Region IV Championships | Fri, May 28 |
| 12 | | Erin Menefee | 4:49.50a | CA | Mt Carmel | San Diego CIF Finals | Sat, May 29 |
| 18. | 11 | | Molly Grabill | 4:49.64a | CA | Rancho Bernardo | San Diego CIF Finals | Sat, May 29 |
| 19. | 10 | | Lyndsy Mull | 4:49.65a | CA | Redondo Union | CIF-SS Masters Meet | Fri, May 28 |
| 20. | 10 | | Savannah Camacho | 4:49.84a | CA | Templeton | CIF-SS Masters Meet | Fri, May 28 |
| 21. | 12 | | Emily Lipari | 4:50.02a | NY | Roslyn | Glenn D Loucks Games (43rd) 2010 | Thu, May 6 |
| 10 | | Maddie Meyers | 4:50.02a | WA | Northwest | 1A State Track and Field Meet (Day 2) | Sat, May 29 |
| 23. | 9 | | Kelly Lawson | 4:50.05a | CA | La Costa Canyon | San Diego CIF Finals | Sat, May 29 |
| 24. | 12 | | Cory Mcgee | 4:50.50 | MS | Pass Christian | MHSAA 4A State Track & Field Championships | Sat, May 15 |
| 25. | 11 | | Catrina McAlister | 4:50.78a | CA | Arcadia | CIF-SS Divisional Finals | Sat, May 22 |
| 26. | 11 | | Molly McNamara | 4:51.13a | NJ | Red Bank Catholic | New Jersey Meet of Champions, All-Group | Thu, Jun 3 |
| 27. | 12 | | Michelle Schebler | 4:51.31a | WY | Natrona county | WHSAA 4A West Regional Track & Field Championships | Sat, May 15 |
| 28. | 11 | | Stephanie Schappert | 4:51.41a | FL | Pope John Paul II | FHSAA 2A Track & Field Championships | Sat, May 1 |
| 29. | 10 | | Abbey Leonardi | 4:51.57a | ME | Kennebunk | Maine Class A State Championship | Sat, Jun 5 |
| 30. | 9 | | Sara Sargent | 4:51.64a | PA | Pennsbury | PIAA District 1 AA & AAA Championships | Fri, May 21 |
| 31. | 12 | | Meg Ryan | 4:51.76a | CT | Fairfield Warden | CIAC Class L State Track & Field Championships | Wed, Jun 2 |
| 32. | 9 | | Amy-Eloise Neale | 4:52.06a | WA | Glacier Peak | 3A District 1 Championships (Day 2) | Fri, May 21 |
| 33. | 12 | | Paige Kvartunas | 4:52.07a | VA | West Springfield | Lake Braddock Hall of Fame Invitational | Sat, Apr 17 |
| 34. | 10 | | Haley Pierce | 4:52.22a | DE | The Tatnall | New Castle County Championships | Sat, May 8 |
| 35. | 12 | | Liga Blyholder | 4:52.26a | MO | Lee's Summit West | MSHSAA Class 4 State Championships Day 2 | Sat, May 29 |
| 36. | 11 | | Joelle Amaral | 4:52.29a | NJ | Randolph | NJSIAA North 1 Group 4 State Sectionals | Sat, May 22 |
| 37. | 11 | | Jennifer Owen | 4:52.45a | CA | West Ranch | California State Meet CIF- Day 2 | Sat, Jun 5 |
| 38. | 11 | | Eleanor Fulton | 4:52.61a | CO | Highlands Ranch | Mullen Runners Runners Roost 2010 | Sat, Apr 10 |
| 12 | | Liberty Miller | 4:52.61a | CA | Simi Valley | CIF-SS Divisional Finals | Sat, May 22 |
| 40. | 11 | | Emma Brink | 4:52.77a | KY | Sacred Heart Academy | Eastern Relays | Sat, Apr 24 |
| 41. | 10 | | Angel Piccirillo | 4:53.11a | PA | Homer Center | West Central Coaches Invitational | Fri, May 7 |
| 42. | 10 | | Rebecca Mehra | 4:53.16a | CA | Palos Verdes | CIF-SS Masters Meet | Fri, May 28 |
| 43. | 12 | | Ruby Roberts | 4:53.27a | WA | Kingston | Washington 2A State Championships (Day 3) | Sat, May 29 |
| 44. | 9 | | Sophie Chase | 4:53.29a | VA | Lake Braddock Secondary | VHSL Northern Region Championships | Fri, May 28 |
| 45. | 12 | | Megan Morgan | 4:53.36a | CA | Torrey Pines | Escondido Invitational | Fri, Apr 30 |
| 46. | 12 | | Shelby Hayes | 4:53.38a | FL | Winter Park | Florida Relays | Fri, Apr 2 |
| 47. | 11 | | Baylee Mires | 4:53.52a | WA | Mead | Washington 4A State Championships (Day 3) | Sat, May 29 |
| 48. | 12 | | Jessica Tonn | 4:53.55a | AZ | Xavier College Preparatory | 5A Division 1 State Championships (Day 2) | Sat, May 15 |
| 49. | 11 | | Michael Rainey | 4:53.74a | CO | Pomona | Nike/Valor Christian Invite 2010 | Sat, Apr 17 |
| 50. | 11 | | Rachel Johnson | 4:53.75a | TX | Plano | UIL 5A State Track and Field Championships | Sat, May 15 |
| 51. | 11 | | Kathryn Fluehr | 4:53.83a | FL | Community School | FHSAA 1A Track & Field Championships | Fri, Apr 30 |
| 52. | 9 | | Haley Meier | 4:53.85a | MI | Grosse Pointe South | MHSAA D1 Track and Field Championships | Sat, Jun 5 |
| 53. | 12 | | Amber Valimont | 4:54.02a | PA | Hempfield Area (7) | PIAA State Championships | Sat, May 29 |
| 54. | 12 | | Anna Bostrom | 4:54.06a | KY | Woodford County | Eastern Relays | Sat, Apr 24 |
| 55. | 9 | | Reagan Anderson | 4:54.14a | DE | The Tatnall | DIAA Meet of Champions | Wed, May 19 |
| 56. | 12 | | Sara Kroll | 4:54.25a | MI | Livonia Churchill | KLAA ASSOCIATION TEAM CHAMPIONSHIP | Tue, May 25 |
| 57. | 10 | | Anna Boyert | 4:54.29a | OH | Medina Senior | OHSAA Division I State Championships | Sat, Jun 5 |
| 58. | 12 | | Kate Desimone | 4:54.32a | IN | Canterbury | IHSAA Girls State Track & Field Finals | Fri, Jun 4 |
| 59. | 11 | | Carly Hamilton | 4:54.58a | OH | Springboro | OHSAA Division I State Championships | Sat, Jun 5 |
| 60. | 9 | | Avery Evenson | 4:54.60 | MI | Hartland | MHSAA Regional 8-1 at Highland Milford | Fri, May 21 |
| 61. | 10 | | Danielle Rodriguez | 4:54.65a | CA | Warren | CIF-SS Masters Meet | Fri, May 28 |
| 62. | 12 | | Kathleen Lautzenheiser | 4:54.76a | VA | Midlothian | Dominion District Track Meet | Wed, May 19 |
| 63. | 11 | | Ashley Roberts | 4:54.80a | CA | Poly (Riverside) | CIF-SS Divisional Finals | Sat, May 22 |
| 64. | 11 | | Erika Fluehr | 4:54.89a | FL | Community School | FHSAA 1A Region 3 Championships | Thu, Apr 22 |
| 65. | 11 | | Colleen Quigley | 4:54.90a | MO | Nerinx Hall | MSHSAA Class 4 State Championships Day 2 | Sat, May 29 |
| 66. | 11 | | Karen Lesiewicz | 4:54.98a | IL | Schaumburg | IHSA Class AAA State Championships - Girls | Sat, May 22 |
| 67. | 11 | | Chloe Schmidt | 4:55.08a | PA | State College Area | PIAA State Championships | Sat, May 29 |
| 68. | 12 | | Julia Otwell | 4:55.20 | MI | Traverse City Central | MHSAA Regional 3-1 at Traverse City Central | Sat, May 22 |
| 69. | 12 | | Colette Whitney | 4:55.21a | NJ | Voorhees | NJSIAA Groups I, III, & Non-Public A Championships | Sat, May 29 |
| 70. | 11 | | Kelsey Smith | 4:55.47a | NH | Exeter | New England Championship | Sat, Jun 12 |
| 71. | 12 | | Diane Robison | 4:55.64a | MO | Parkway Central | MSHSAA Class 4 District 2 | Sat, May 15 |
| 72. | 11 | | Hayley McMahon | 4:55.68a | NY | Arlington | Glenn D Loucks Games (43rd) 2010 | Thu, May 6 |
| 73. | 11 | | Jaye Buchbinder | 4:55.77a | CA | Chadwick | CIF-SS Masters Meet | Fri, May 28 |
| 9 | | Katie Knight | 4:55.77a | WA | North Central | Washington 3A State Championships (Day 3) | Sat, May 29 |
| 75. | 11 | | Madeline Rathbun | 4:55.78a | WA | Lakeside (Seattle) | Washington 3A State Championships (Day 3) | Sat, May 29 |
| 76. | 12 | | Emily LaValley | 4:56.17a | CO | Classical Academy | Chandler Rotary Seeded Invitational | Sat, Mar 27 |
| 77. | 9 | | Sarah Fakler | 4:56.18a | AZ | Xavier College Preparatory | Chandler Rotary Seeded Invitational | Sat, Mar 27 |
| 78. | 11 | | Samantha Ralstin | 4:56.20a | CA | Oak Ridge | Meet of Champions | Sat, May 1 |
| 79. | 11 | | Katie Betts | 4:56.36a | OH | Stow-Munroe Falls | OHSAA Northeast - Ravenna Division I District Track | Fri, May 21 |
| 80. | 11 | | Chloe Maleski | 4:56.40a | NH | Keene | NHIAA Meet of Champions | Sat, Jun 5 |
| 81. | 12 | | Jacque Taylor | 4:56.41a | CA | Casa Grande | California State Meet CIF- Day 2 | Sat, Jun 5 |
| 82. | 12 | | Elizabeth Locke | 4:56.43a | NJ | Kingsway Regional | NJSIAA Groups I, III, & Non-Public A Championships | Sat, May 29 |
| 83. | 12 | | Kelsey Seymour | 4:56.50a | PA | Central Cambria | West Central Coaches Invitational | Fri, May 7 |
| 84. | 11 | | Tansey Lystad | 4:56.52a | WA | Juanita | Washington 3A State Championships (Day 3) | Sat, May 29 |
| 85. | 12 | | Amanda Russell | 4:56.54a | TX | CP Vista Ridge | UIL 5A State Track and Field Championships | Sat, May 15 |
| 86. | 12 | | McKinzie Schulz | 4:56.60a | IL | Lisle (Benet Academy) | IHSA Class AAA State Championships - Girls | Sat, May 22 |
| 87. | 11 | | Samantha Levin | 4:56.63a | MO | Ladue Horton Watkins | MSHSAA Class 4 District 2 | Sat, May 15 |
| 88. | 12 | | Kayleigh Perry | 4:56.66a | PA | Eastern Lebanon | PIAA State Championships | Sat, May 29 |
| 11 | | Lindsay Clark | 4:56.66a | MI | Walled Lake Western | MHSAA D1 Track and Field Championships | Sat, Jun 5 |
| 90. | 10 | | Margo Malone | 4:56.83a | PA | North Hills | PIAA State Championships | Sat, May 29 |
| 91. | 10 | | Chris Kartchner | 4:56.88a | CO | Pomona | Nike/Valor Christian Invite 2010 | Sat, Apr 17 |
| 92. | 9 | | Emily Waligurski | 4:57.03a | NY | Onteora | Glenn D Loucks Games (43rd) 2010 | Thu, May 6 |
| 93. | 12 | | Nicky Akande | 4:57.040a | GA | Collins Hill | GHSA Girls AAAAA State Championships | Sat, May 8 |
| 94. | 9 | | Bridget Blake | 4:57.07a | FL | Freedom (Orlando) | Florida Relays | Fri, Apr 2 |
| 11 | | Jessica Hoover | 4:57.07a | OH | Hilliard Davidson | OHSAA Division I State Championships | Sat, Jun 5 |
| 96. | 11 | | Annie LeHardy | 4:57.26a | VA | Hidden Valley | VHSL Region IV Championships | Fri, May 28 |
| 97. | 10 | | Amy Weissenbach | 4:57.29a | CA | Harvard-Westlake | CIF-SS Divisional Finals | Sat, May 22 |
| 98. | 11 | | Jacy Christiansen | 4:57.34a | NH | Mascenic Regional | NHIAA Class M & S Track Championships | Sat, May 29 |
| 99. | 12 | | Katherine Walker | 4:57.37a | VA | Brooke Point | Lake Braddock Hall of Fame Invitational | Sat, Apr 17 |
| 100. | 12 | | Brook Handler | 4:57.39a | MI | Rochester | 51st Annual Varsity Oakland County Championships | Fri, May 28 |
| 101. | 9 | | Marissa Ruskan | 4:57.41a | NJ | Bridgewater-Raritan | New Jersey Meet of Champions, All-Group | Thu, Jun 3 |
| 102. | 9 | | Courtney Ackerman | 4:57.48a | IL | Winnetka (New Trier) | IHSA Class AAA State Championships - Girls | Sat, May 22 |
| 10 | | Allison Sturges | 4:57.48a | CA | Mountain View | California State Meet CIF- Day 2 | Sat, Jun 5 |
| 104. | 11 | | Gabrielle Anzalone | 4:57.50 | MI | Grand Blanc | MHSAA Regional 3-1 at Traverse City Central | Sat, May 22 |
| 12 | | Juli Accurso | 4:57.50a | OH | Miami East | OHSAA Division III State Championships | Sat, Jun 5 |
| 106. | 9 | | Kendra Weitz | 4:57.60a | WA | Shadle Park | Washington 3A State Championships (Day 3) | Sat, May 29 |
| 107. | 12 | | Jana Stolting | 4:57.64a | FL | Maclay | Florida Relays | Fri, Apr 2 |
| 108. | 11 | | Krista Menghini | 4:57.67a | MO | St Josephs Academy | MSHSAA Class 4 District 2 | Sat, May 15 |
| 109. | 12 | | Gabby Levac | 4:57.77a | WI | Arrowhead | WIAA D1, D2, & D3 Track & Field State Championships | Sat, Jun 5 |
| 110. | 12 | | Julie Jablonski | 4:57.82a | NJ | Hopewell Valley Central | NJSIAA Groups I, III, & Non-Public A Championships | Sat, May 29 |
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(Total stats: 28,155)
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