| 1. | - | | kirlene Roberts Semoy Hackett Nyoka Cole Tia Rolle | 44.65a | MO | Lincoln (MO) | Billy Hayes Invitational | Fri, May 7 |
| 2. | - | | Sydney Smith Wanda Hutson Joella Foster Kim Prather | 45.19a | TX | Abilene Christian | NCAA Division II Championships | Sat, May 29 |
| 3. | - | | Rosemarie Carty Shermaine Williams Lakaevia Tyler Monique Kelly | 45.24a | NC | Johnson C. Smith | NCAA Division II Championships | Sat, May 29 |
| 4. | - | | Keisha Parris Barbara Pierre Sheena Johns Angelique Smith | 45.53a | NC | St Augustine's | NCAA Division II Championships | Sat, May 29 |
| 5. | - | | Linnelle Clark Becca Schmidt Kelsey Leonard Brittany Henderson | 45.56a | MN | Minnesota State Mankato | NCAA Division II Championships | Sat, May 29 |
| 6. | - | | Tiffany Moore Portia Wilson Shankevia Burke Raven Wilson | 45.66a | GA | Fort Valley State | NCAA Division II Championships | Sat, May 29 |
| 7. | - | | Relay Team | 45.90a | CA | CS Los Angeles | CSULA Last Chance Qualifier | Sat, May 15 |
| 8. | - | | Kristyn Nelson Nicketa Coombs Mishay Weber Kristen Stewart | 46.03a | ND | University of Mary | NCAA Division II Championships | Sat, May 29 |
| 9. | - | | Relay Team | 46.09a | CA | CS Dominguez Hills | CSULA Last Chance Qualifier | Sat, May 15 |
| 10. | - | | Aisha Adams Celethia Byrd Sara Hooker Makayla Myers | 46.17a | TX | Angelo State | NCAA Division II Championships | Sat, May 29 |
| 11. | - | | Christine Merrill Kathleen Hitchens Jaqueline Rose Kelly Fogarty | 46.29a | CA | UC San Diego | NCAA Division II Championships | Sat, May 29 |
| 12. | - | | Saquenda Dallas Tierra Blue Crystal Shepherd Ashley McCoy | 46.44a | NC | North Carolina Central | CCU Invitational | Sat, Mar 13 |
| 13. | - | | Lindsey Grasmick Indira Spence Jazmine Ralph Amanda Doyle | 46.74a | CO | Adams State | CSM Last Chance Meet | Sun, May 16 |
| 14. | - | | Cathryn Humphries Marta Scheiwe Circe Cansino Jazmin Williams | 46.79a | MI | Hillsdale | Gina Relays | Sat, Apr 24 |
| 15. | - | | Tonisha Delorch Alexandria Payne Ebone Washington Kristina Record | 46.83a | KY | Kentucky State | Billy Hayes Invitational | Fri, May 7 |
| 16. | - | | Jasmine Sanford Corie Chuning Tyrahnique Thomas Jenny Blair | 46.85a | MO | Southwest Baptist | MIAA Outdoor Championships | Sun, May 9 |
| 17. | - | | Relay Team | 46.90a | WA | Western Washington | Mt. SAC Relays | Sat, Apr 17 |
| 18. | - | | Johniqua Stafford Keahna Wheatland Kyley Jorgensen Tiffany Richardson | 46.96a | FL | Nova Southeastern | Drake Relays | Sat, Apr 24 |
| 19. | - | | Relay Team | 47.00a | VA | Virginia State | Carolina Qualifier | Sat, May 8 |
| 20. | - | | Qiauna Fair Angela Graham Candace St. Louis SherryAnn Baggoo | 47.07a | NM | New Mexico Highlands | CSM Last Chance Meet | Sun, May 16 |
| 21. | - | | Taccara Bivens Cherrisa Brockington Jasmine Dalton Sherrina Lewis | 47.20a | GA | Albany State | Alice Coachman Invitational | Sat, Apr 3 |
| - | | Sahnique CastellA Sarah Hill Letecia Taylor Ashely Bell | 47.20a | CT | Southern Connecticut | Northeast-10 Championships | Sat, May 1 |
| 23. | - | | Relay Team | 47.27a | IN | Indianapolis | Cardinal Twilight | Fri, May 14 |
| 24. | - | | Relay Team | 47.30a | MI | Grand Valley State | Illinois Twilight Invite | Fri, Apr 30 |
| 25. | - | | Raquisha Givens Laquita Daniel Ibukunoluwa Awoyale Shelisa Crawford | 47.40a | GA | Columbus State (GA) | Georgia Tech Invitational | Sat, May 15 |
| 26. | - | | Sharikka Finley-Moise Nicole Giaquinto Katrina Lutkus Ashley Zielinski | 47.42a | MA | Massachusetts-Lowell | Northeast-10 Championships | Sat, May 1 |
| 27. | - | | Relay Team | 47.50a | PA | Slippery Rock | PSAC Championships | Sat, May 15 |
| 28. | - | | Relay Team | 47.69a | MN | Winona State | Warrior Open | Sat, May 1 |
| 29. | - | | Relay Team | 47.71a | MD | Bowie State | Penn Relays | Sat, Apr 24 |
| 30. | - | | Colleen Bednar Kaitlyn Holland Whitney Johnson Andrea Boyd | 47.76a | OH | Lake Erie | Billy Hayes Invitational | Fri, May 7 |
| - | | Latrice Johnson Alex Lopez-Rogina Kimaya Johnson Rachel Joseph | 47.76a | AL | Alabama-Huntsville | Georgia Tech Invitational | Sat, May 15 |
| 32. | - | | Relay Team | 47.77a | NC | Winston-Salem State | Penn Relays | Sat, Apr 24 |
| 33. | - | | Stefanie Dittmar Sarah Kathrein McKenzie Redberg Lacey Muesec | 47.81a | OR | Western Oregon | GNAC Outdoor Championships | Sat, May 15 |
| 34. | - | | Relay Team | 47.85a | TX | West Texas A&M | LSC Championships | Sun, May 9 |
| 35. | - | | Ariel Whitney Trameika Thomas Tokunbo Adeniji Brooke Gamble | 47.88a | CA | Cal Poly Pomona | Trojan Invitational | Sat, Mar 20 |
| 36. | - | | Stephany Johnson Angela Selby Lori Mortenson Lindsay Lettow | 47.89a | MO | Central Missouri | Drake Relays | Sat, Apr 24 |
| 37. | - | | Courtney Martin Katie Craven Amanda Spickler Amanda Dubs | 48.04a | PA | Shippensburg | PSAC Championships | Sat, May 15 |
| 38. | - | | Relay Team | 48.08a | TX | Texas A&M-Kingsville | LSC Championships | Sun, May 9 |
| 39. | - | | Skyieshia Bean Jalessia Coleman Angela Graves Cierra Harris | 48.10a | GA | Paine | Alice Coachman Invitational | Sat, Apr 3 |
| 40. | - | | Brittany Johnson Alicia Chambers Carrie Thomas Stefeny Butler | 48.13a | CA | San Francisco State | Johnny Mathis Invitational | Sat, Apr 3 |
| 41. | - | | Kristin Slack Brooke Mathews Sarah Messner Shante Grayer | 48.16a | PA | Kutztown | PSAC Championships | Sat, May 15 |
| 42. | - | | Relay Team | 48.23a | IL | Lewis | Illinois Twilight Invite | Fri, Apr 30 |
| 43. | - | | Relay Team | 48.24a | CO | Colorado State-Pueblo | CSU-Pueblo Invitational | Sat, Apr 17 |
| - | | Ana Kidder Steph Tinney Steph Abbott Yuvonne Henry | 48.24a | OH | Ashland | Ashland Alumni Invitational | Sat, Apr 24 |
| 45. | - | | Jody-Ann Coore Molly Belling Kayla Murphy Maja Mihalinec | 48.25a | NE | Nebraska - Omaha | MIAA Outdoor Championships | Sun, May 9 |
| 46. | - | | Relay Team | 48.26a | NC | Shaw | Penn Relays | Sat, Apr 24 |
| - | | Ufuoma Egbikuuadje Brittne Showers Derrhea Mcliechedy Whitney Anderson | 48.26a | CA | CS Stanislaus | CCAA Championships | Sat, May 8 |
| 48. | - | | Brittany Simmons Amanda Davis Jill Hooker Lanneka Brewton | 48.28a | TN | King College | NCCAA Championships | Sat, May 8 |
| 49. | - | | Trinna Miranda Lisette Peterson Emily Quatier Chrystal Sims | 48.34a | WA | Seattle Pacific | GNAC Outdoor Championships | Sat, May 15 |
| 50. | - | | Mary Jo Swann Josie McCracken Jalexis Peterson Rosalyn Nelson | 48.37a | KS | Pittsburg State (KS) | FHSU Multi-Event Open / Quad Meet | Sat, Apr 3 |
| 51. | - | | Jessica Johnson Erica Minor Keiana Richardson Alquandra Slater | 48.40a | AL | Concordia-Selma | Alice Coachman Invitational | Sat, Apr 3 |
| - | | Lauren Hannan Jasmine Johnson Adrienne Dieter Lauren Ventrella | 48.40a | PA | East Stroudsburg | PSAC Championships | Sat, May 15 |
| 53. | - | | Michelle Burley Lindsey Witteman Aimee Rodgers Nicole Cooper | 48.46a | CA | Chico State | CCAA Championships | Sat, May 8 |
| 54. | - | | Shemia Barnes Saleena Green Jasmine Rich Famatta Lewis | 48.53a | DC | District of Columbia | Delaware State Invitational | Sat, May 1 |
| 55. | - | | Relay Team | 48.55a | MO | Northwest Missouri State | Northwest Open | Sat, Apr 3 |
| - | | Jessica Keesling Kendra Mooberry Ashley Berg Kristina Anderson | 48.55a | MN | Minnesota State Moorhead | Cobber Twilight | Tue, Apr 20 |
| 57. | - | | Mackenzie Lauro Sam Smarkola Brigid Gallagher Miriam Hughes | 48.58a | PA | West Chester | PSAC Championships | Sat, May 15 |
| 58. | - | | Ashley Fanelli Meghan Finney Trae Patch Monique Fair | 48.62a | NE | Chadron State | RMAC Outdoor Championships | Tue, May 11 |
| 59. | - | | Emily Allis Briana Stewart Jazmin White Kristen Lee | 48.64a | CA | Academy of Art Univ | UC Davis Classic | Sat, Mar 20 |
| - | | Valarie Jasper Jasmine Claggett Kelsey Spang Daytona Maher | 48.64a | WV | West Virginia Wesleyan | WVIAC Championships | Sat, May 1 |
| - | | Renae Weaver Marqueita Marisette Kayce Yelliott Brooke Kent | 48.64a | KS | Emporia State | MIAA Outdoor Championships | Sun, May 9 |
| 62. | - | | Christabel Leonce Latoya Tidwell Lindsay Brady Melissa Grammer | 48.70a | ID | Northwest Nazarene | GNAC Outdoor Championships | Sat, May 15 |
| 63. | - | | Kristen Saggio Olivia Lent Cassie Urbauer Ashley White | 48.74a | WV | Wheeling Jesuit | WVIAC Championships | Sat, May 1 |
| 64. | - | | Alyssa Erspamer Brittnee Balbierz Melissa Christensen Catherine Angeli | 48.76a | MI | Northern Michigan | Northwood Invite | Fri, Apr 30 |
| 65. | - | | Brittany Pratt Lydia Powell Erin Barnett Shawnee Carnett | 48.77a | WV | Concord | WVIAC Championships | Sat, May 1 |
| 66. | - | | Relay Team | 48.78a | TX | Tarleton State | LSC Championships | Sun, May 9 |
| 67. | - | | Tia Cook JeAnna Sheppard Danielle Oliver Kelly McKay | 48.83a | MO | Missouri Southern | MIAA Outdoor Championships | Sun, May 9 |
| - | | Laurie Ajovan Tamika Taylor Maddy Outman Brianna Liebold | 48.83a | PA | Indiana U of PA | PSAC Championships | Sat, May 15 |
| 69. | - | | Montreal Barnette India Golden Jessica McDowell Kyera Tennyson | 48.89a | NC | North Carolina-Pembroke | Johnson C. Smith Invitational | Sat, Apr 10 |
| - | | Relay Team | 48.89a | SC | Benedict | SIAC Championship | Sat, Apr 17 |
| - | | Stephanie Orji Lorraine Laster Georgia Anderson Isabelle Cayo | 48.89a | PA | Cheyney U of PA | Eagle Twilight Invitational | Thu, Apr 29 |
| 72. | - | | Relay Team | 48.95a | SC | Claflin | SIAC Championship | Sat, Apr 17 |
| - | | Anisha Barbee Stephanie Wilson Maya Stewart Shamaka Adams | 48.95a | SC | Limestone | USC Upstate Invitational | Sat, Apr 24 |
| 74. | - | | Lauren Keiser Kiera Benson Erin Glover Hillary Hurst | 48.96a | CO | Colorado School of Mines | Jack Christiansen Invite | Sat, Apr 24 |
| 75. | - | | Tabitha Kreutzer Sally Studley Heather Wills Jessie Golden | 48.99a | NE | Nebraska-Kearney | UNK Twilight | Fri, Apr 30 |
| 76. | - | | Olivia Richardson Chelsea Cavanaugh Nina Gladysiewski Amanda Ponsonby | 49.00a | PA | Seton Hill | WVIAC Championships | Sat, May 1 |
| 77. | - | | Relay Team | 49.11a | PA | California U of PA | PSAC Championships | Sat, May 15 |
| 78. | - | | Kristen Fleharty Kelsey Martin Whitney Taylor Ashley Cornett | 49.14a | KS | Fort Hays State | MIAA Outdoor Championships | Sun, May 9 |
| 79. | - | | Relay Team | 49.17a | PA | Lincoln U (PA) | Penn Invite | Sat, Apr 3 |
| 80. | - | | Haley Watts Lauren Pratt Lilya Piskunova Stacy Stanush | 49.22a | TX | Incarnate Word | UIW Invitational | Sat, Feb 27 |
| 81. | - | | Katrina Biermann Jennifer Zweifel Lisa Kucharski Kaci Sargent | 49.24a | MO | Truman State | Dewey Allgood Invitational | Sat, Apr 17 |
| 82. | - | | Relay Team | 49.28a | MO | Missouri S&T | Bison Invitational | Sat, Apr 3 |
| 83. | - | | Ebony Lewis Jakesia King Shagayla Petty Charnita Hollands | 49.41a | TX | Texas A&M-Commerce | Bobby Lane UT-Arlington Invitational | Sat, Mar 27 |
| 84. | - | | Janay Barconey Blake Terry Angel Laws Jamila McKenzie | 49.42a | AL | Tuskegee | NCAA Div II South Regional Meet | Sat, May 1 |
| 85. | - | | Corie Schattauer Brittainy Chown Melissa Murillo Olivia Juarez | 49.50a | CA | Humboldt State | CCAA Championships | Sat, May 8 |
| 86. | - | | Casey Hagen Hannah Selke Erin Vigil Jourdan Otis | 49.53a | CO | Western State | Don Kirby Memorial Invitational | Sat, May 1 |
| 87. | - | | Tylena Murray Lauren Edelman Cassie Snider Jenna Knight | 49.55a | PA | Lock Haven | PSAC Championships | Sat, May 15 |
| 88. | - | | Relay Team | 49.58a | MI | Saginaw Valley State | Stan Lyons Invitational | Sat, Apr 24 |
| 89. | - | | Lindsay Hart Taylor Allmon Alicia Gieck Breanna Jones | 49.64a | CO | Mesa State | RMAC Outdoor Championships | Tue, May 11 |
| 90. | - | | Raven Clay Stephanie Charnigo Lisa Kaulfersch Lindsey Schmitmeyer | 49.65a | OH | Findlay | GLIAC Championships | Fri, May 7 |
| - | | Ardrienna Everett Elisha Harris Meagan Friess Lauren Laichak | 49.65a | AK | Alaska-Anchorage | Oxy Invite | Sat, May 8 |
| 92. | - | | Relay Team | 49.67a | MN | Minnesota-Duluth | Lee Krough Open | Sat, Apr 10 |
| 93. | - | | Relay Team | 49.72a | MN | Concordia-St. Paul | Capitol City Championships | Sat, May 1 |
| 94. | - | | Relay Team | 49.75a | AL | Stillman | SIAC Championship | Sat, Apr 17 |
| 95. | - | | Relay Team | 49.80a | GA | Clark Atlanta | SIAC Championship | Sat, Apr 17 |
| 96. | - | | Cammelle Ward Rachel Hettinger Amanda Watson Sara Snider | 49.83a | MI | Northwood (MI) | Northwood Invite | Fri, Apr 30 |
| 97. | - | | Re'Jeania Evans Joelle Purinton Sarah Solsbee Krishaun Hall | 49.96a | SC | Anderson (SC) | USC Upstate Invitational | Sat, Apr 24 |
| 98. | - | | Relay Team | 50.00a | AR | Harding | NCAA Div II South Regional Meet | Sat, May 1 |
| 99. | - | | Erika Halle Elissa Adams Britney Derhak Justine Simons | 50.06a | MT | Montana State-Billings | UNLV Track Classic | Sat, Mar 6 |
| 100. | - | | Relay Team | 50.08a | KY | Bellarmine | Eastern Kentucky University Open | Fri, Apr 16 |
| 101. | - | | Relay Team | 50.14a | SD | Northern State (SD) | Howard Wood Relays | Sat, May 1 |
| 102. | - | | Relay Team | 50.21a | WA | Central Washington | JD Shotwell Invitational | Sat, Apr 3 |
| 103. | - | | Stacey Bernetski Whitney Savoy Maitlyn Conaboy Chrissy Savage | 50.27a | PA | Millersville | PSAC Championships | Sat, May 15 |
| 104. | - | | Relay Team | 50.32a | SD | Augustana (SD) | Howard Wood Relays | Sat, May 1 |
| - | | Relay Team | 50.32a | MN | St Cloud State | Warrior Open | Sat, May 1 |
| 106. | - | | Relay Team | 50.40a | OH | Tiffin | Wake Forest Open | Sat, Mar 20 |
| 107. | - | | Alicia Allen Sarah Merkel Erica Blythe Jenny Merkel | 50.60a | IN | St Joseph's (IN) | GLVC Outdoor Championships | Sat, May 8 |
| 108. | - | | Danielle Wheeler Vlada Shelkova Olivia Dyson Angela Miller | 50.85a | MA | Stonehill | Northeast-10 Championships | Sat, May 1 |
| 109. | - | | Monika Czurylo Natalie Caldwell Melissa Kimball Amy Varsell | 50.91a | MA | Bentley | Northeast-10 Championships | Sat, May 1 |
| 110. | - | | Relay Team | 50.94a | MN | Bemidji State | NSU Open | Fri, Apr 2 |
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(Total stats: 137)
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