| 1. | - | | Takeia Pinckney
Semoy Hackett
Rebecca Alexander
Kimberlyn Duncan | 42.68a | LA | LSU | NCAA Division I Outdoor Track and Field Championships | Wed, Jun 6 |
| 2. | - | | V'Alonee Robinson
Cece Williams
Kai Salvon
Nivea Smith | 43.67a | AL | Auburn | SEC Outdoor Track & Field Championships | Thu, May 10 |
| 3. | - | | Darshay Davis
Alishea Usery
Ugonna Ndu
Ebony Eutsey | 43.99a | FL | Florida | Pepsi Florida Relays | Sat, Apr 7 |
| 4. | - | | Gwendolyn Flowers
Regina George
Tiffany Hines
Whitney Jones | 44.04a | AR | Arkansas | NCAA Division I Outdoor Track and Field Championships | Wed, Jun 6 |
| 5. | - | | Ashley Harris
Brittany Jones
Martinique Octave
Kia Jackson | 44.26a | TN | Tennessee | NCAA Division I Outdoor Track and Field Championships | Wed, Jun 6 |
| 6. | - | | Asia Delaney
Kelsey McCorkle
Vashti Bandy
Amber Allen | 45.06a | SC | South Carolina | NCAA Championships-East Preliminary Round | Sat, May 26 |
| 7. | - | | Shari Russell
Jasmine Williams
Monica Williams
Kristin Bridges | 45.14a | MS | Mississippi | NCAA Championships-East Preliminary Round | Sat, May 26 |
| 8. | - | | Brittany Covington
Jody-Ann Muir
Rochelle Farquharson
Erica Bougard | 45.53a | MS | Mississippi State | SEC Outdoor Track & Field Championships | Thu, May 10 |
| 9. | - | | Tamyah Pipkin
Keilah Tyson
Shiara Robinson
Kayla Parker | 45.59a | KY | Kentucky | Pepsi Florida Relays | Sat, Apr 7 |
| 10. | - | | Audra Frimpong
Camilla Armstead
Sarah Thomas
Shani Chandler | 46.19a | AL | Alabama | SEC Outdoor Track & Field Championships | Thu, May 10 |
