| 1. | - | | DaQuan Brown
Darrell Chester
Marciellian Gardner
Deontre Gray | 41.86a | IN | Lawrence Central | IHSAA State Finals | Sat, Jun 2 |
| 2. | - | | Jaron Clark
Korey Rogan
Corey Conway
Jordan Williams | 41.99a | IN | North Central (Indianapolis) | IHSAA State Finals | Sat, Jun 2 |
| 3. | - | | Tre Roby
Bobby Mulligan
Terry McLaurin
Malcom Dotson | 43.27a | IN | Indianapolis Cathedral | All-Catholic Championship | Fri, Apr 27 |
| 4. | - | | Zachary Gapinski
Jalu Obeime
Shine Duncan
Lavante Bellamy | 43.77a | IN | Brebeuf Jesuit Prep | All-Catholic Championship | Fri, Apr 27 |
| - | | Jabari Adkins
Damon Graham
Camare Hairston
Maleek Hairston | 43.77a | IN | Arsenal Technical | Boys City | Wed, May 9 |
| 6. | - | | Dylan Gray
Nick Siderys
Brent Kelly Hooks
Ryan Kleinschmidht | 44.32a | IN | Bishop Chatard | All-Catholic Championship | Fri, Apr 27 |
| 7. | - | | Nick Rodriguez
Christian Neal
Kennan Johnson
Kailen Griffin | 44.76a | IN | Lawrence North | MIC | Fri, Apr 27 |
| - | | Keith Anderson
Emanual Evans
Randy Morton
Shaquille Williams | 44.76a | IN | Broad Ripple | IHSAA Sectional (Boys) | Thu, May 17 |
| 9. | - | | Kyle Bingham
Jermaine Briggs
Trenton Keeling
Joey Martin | 45.64a | IN | Indiana School For The Deaf | Boys City | Wed, May 9 |
| 10. | - | | David Kilkenny
Chris Gregory
John Havlik
AJ Sood | 46.80a | IN | Park-Tudor | PT Showcase | Fri, Apr 13 |
| 11. | - | | Blake Ber
Brian Carter
Griffin Offenhauser
Ben Osborne | 50.07a | IN | Heritage Christian | Boys City | Wed, May 9 |
| 12. | - | | Jacob Carter
Xavier Green
Louis Rogers-Rose
Michael Shepard | 54.01a | IN | Irvington | Greenfield-Central Invitational | Fri, May 4 |
