| 1. | 12 | | Alex Meier | 44.99a | IN | Munster | IHSAA Regional (Girls) | Tue, May 22 |
| 2. | 12 | | Kortney Mabone | 45.83a | IN | Gary West Side | IHSAA Girls State Finals | Fri, Jun 1 |
| 3. | 11 | | Kassidy Swenson | 46.13a | IN | Valparaiso | IHSAA Regional (Girls) | Tue, May 22 |
| 4. | 11 | | Keyera Lige | 46.38a | IN | Bowman Leadership Academy | IHSAA Regional (Girls) | Tue, May 22 |
| 5. | 11 | | Tori Nida | 46.74a | IN | Lowell | Munster Invitational | Fri, Apr 27 |
| 6. | 9 | | Allison Vogeler | 46.78a | IN | New Prairie | IHSAA Regional (Girls) | Tue, May 22 |
| 7. | 11 | | Victoria Nida | 46.88a | IN | Lowell | IHSAA Regional (Girls) | Tue, May 22 |
| 8. | 12 | | Andrea Alvarez | 47.44a | IN | Lake Central | IHSAA Regional (Girls) | Tue, May 22 |
| 9. | 12 | | Shermika Winston | 47.48a | IN | Merrillville | IHSAA Regional (Girls) | Tue, May 22 |
| 10. | 11 | | Cassidy Swenson | 47.53a | IN | Valparaiso | West Lafayette Relays | Sat, Apr 21 |
| 11. | 11 | | Shakiea Boyd | 48.75a | IN | Portage | Chesterton & Merrillville & Portage | Tue, Apr 17 |
| 12. | 9 | | Madison Kurtz | 48.76a | IN | Portage | Valparaiso | Tue, May 1 |
| 13. | 10 | | Trina Coleman | 48.95a | IN | Morgan Township | IHSAA Regional (Girls) | Tue, May 22 |
| 14. | 10 | | Joli Jungels | 49.76a | IN | Kankakee Valley | IHSAA Regional (Girls) | Tue, May 22 |
| 15. | 10 | | Lindsay Heavner | 50.40a | IN | Wheeler | Greater South Shore Conference (Girls) | Tue, May 8 |
| 16. | 11 | | Stephanie Samuels | 50.52a | IN | Merrillville | Lake Central & Valparaiso & Merrillville | Tue, Apr 24 |
| 17. | 12 | | Katelyn Schwenk | 50.98a | IN | Oregon-Davis | IHSAA Regional (Girls) | Tue, May 22 |
| 18. | 12 | | Desiree Swartz | 51.17a | IN | River Forest | IHSAA Regional (Girls) | Tue, May 22 |
| 19. | 9 | | Harley Sutton | 51.23a | IN | Hobart | Hobart/Munster | Thu, May 3 |
| 20. | 9 | | Melissa Bailey | 51.42a | IN | Winamac Community | IHSAA Regional (Girls) | Tue, May 22 |
| 21. | 9 | | Hannah Pixely | 51.94a | IN | Valparaiso | West Lafayette Relays | Sat, Apr 21 |
| 22. | 10 | | Dori Sotirovska | 52.06a | IN | Crown Point | West Lafayette Relays | Sat, Apr 21 |
| 23. | 10 | | Alivia Kruger | 52.30a | IN | West Central | Midwest Conference Championship | Fri, May 4 |
| 24. | 11 | | Melissa Bennett | 52.64c | IN | Lowell | Lowell/Highland/KV | Thu, May 3 |
| 25. | 11 | | DeAnna Russel | 52.91a | IN | Lowell | IHSAA Sectional (Girls) | Tue, May 15 |
| 26. | 11 | | Kenyata Todd | 52.98a | IN | Bowman Leadership Academy | Don Lukens / Lady Knight Invitational | Fri, Apr 27 |
| 27. | 10 | | Samantha Massoels | 53.23a | IN | Rensselaer Central | Hoosier Conference | Fri, May 11 |
| 28. | 9 | | Cariana Young | 53.39a | IN | Michigan City | Pike Invitational | Fri, May 4 |
| 29. | 9 | | Danielle Harmston | 53.52a | IN | Lowell | Griffith/Munster/Lowell | Tue, Apr 17 |
| 30. | 12 | | Katy Anspach | 53.68a | IN | Winamac Community | Midwest Conference Championship | Fri, May 4 |
| 31. | 9 | | Bella Santana | 53.97a | IN | Chesterton | West Lafayette Relays | Sat, Apr 21 |
| 32. | 11 | | Nicole Skopelja | 54.40a | IN | Wheeler | Greater South Shore Conference (Girls) | Tue, May 8 |
| 33. | 10 | | A'Leah Scott | 54.55a | IN | Merrillville | Chesterton & Merrillville & Portage | Tue, Apr 17 |
| 34. | - | | Annette January | 54.56a | IN | Bowman Leadership Academy | Don Lukens / Lady Knight Invitational | Fri, Apr 27 |
| 35. | 10 | | Grace Wylie | 54.83a | IN | Crown Point | West Lafayette Relays | Sat, Apr 21 |
| 36. | 12 | | Ali Johnson | 54.84a | IN | Portage | Valparaiso | Tue, May 1 |
| 37. | 12 | | Hannah Levendoski | 55.11a | IN | Michigan City | Pike Invitational | Fri, May 4 |
| 38. | 12 | | Tina Anderson | 55.34c | IN | Highland | Griffith @ Highland | Tue, Apr 10 |
| 39. | 9 | | Karina Pietrzak | 55.73a | IN | Highland | IHSAA Girls Sectional | Tue, May 15 |
| 40. | 10 | | Makayla Bushman | 55.81a | IN | West Central | Midwest Conference Championship | Fri, May 4 |
| 41. | 11 | | Megan Litteral | 56.32a | IN | Lowell | Cabin Fever Classic | Sat, Mar 31 |
| 42. | 10 | | Shantelle Walker | 56.97a | IN | Lowell | Chesterton Relays | Sat, Apr 14 |
| 43. | 9 | | Skyler Lewis | 57.21a | IN | Lowell | Lowell/Andrean | Tue, Apr 24 |
| 44. | 11 | | Tamara Lofton | 58.65a | IN | Lew Wallace | Roosevelt/Lew Wallace @ Wheeler | Tue, Apr 24 |
| 45. | 9 | | Marissa Sullivan | 60.69a | IN | Chesterton | West Lafayette Relays | Sat, Apr 21 |
| 46. | 12 | | LaQuita Hardy | 61.99a | IN | Gary Roosevelt | Roosevelt/Lew Wallace @ Wheeler | Tue, Apr 24 |
| 47. | 10 | | Caitlyn Edinger | 63.24c | IN | Bishop Noll Institute | GSSC Quad | Mon, Apr 2 |
| 48. | 11 | | Sarah Rebey | 63.44c | IN | Highland | Griffith @ Highland | Tue, Apr 10 |
| 49. | 11 | | Lindsay Ward | 64.04c | IN | Lowell | Bowman/Gavit/Lake Station/Lowell | Tue, Apr 3 |
| 50. | 11 | | Ashley Faucault | 64.14c | IN | Highland | Munster @ Highland | Tue, Apr 24 |
| 51. | 11 | | Carolyn Fiegle | 66.14c | IN | Highland | Griffith @ Highland | Tue, Apr 10 |
| 52. | 10 | | Jasmine Johnson | 67.29a | IN | Portage | Michigan City & LaPorte | Tue, Apr 24 |
| 53. | - | | Ta'Ti'Ana Jones | 73.33a | IN | Portage | Wheeler & Boone Grove | Thu, Apr 5 |
| 54. | 12 | | Allexys Woodard | 73.42a | IN | Highland | Highland @ Chesterton | Thu, Apr 5 |
