| 1. | - | | Shanica Johnson
Chelsey Hargrave
Tamilia Wright
Abigail Bost | 1:44.27a | NC | Walter Williams | NCHSAA 3A State Meet | Fri, May 18 |
| 2. | - | | Raven Hamilton
Staci Green
Myra Henderson
Kylie McMillan | 1:45.58a | NC | Southern Guilford | NCHSAA 3A State Meet | Fri, May 18 |
| 3. | - | | Kendale Burke
Olivia Lowman
Carlecia Spivey
Kamesha Tatum | 1:47.00a | NC | Douglas Byrd | NCHSAA 3A State Meet | Fri, May 18 |
| 4. | - | | Katrina Collins
Janice Coffen
Nicole Chestnut
Qizeah Jackson | 1:48.50 | NC | Westover Senior | Cape Fear Valley Meet I | Thu, Mar 8 |
| 5. | - | | Relay Team | 1:48.64a | NC | Asheboro | NCHSAA 3A Regional Meet | Sat, May 12 |
| 6. | - | | Relay Team | 1:50.50 | NC | Northeast Guilford | Mid-Piedmont 3A Conference Championship | Tue, May 1 |
| 7. | - | | Relay Team | 1:51.41a | NC | Eastern Alamance | NCHSAA 3A Regional Meet | Sat, May 12 |
| 8. | - | | Tyeshia McKeithan
Tiara Bland
Deshele Sumpter
Brianna Taylor | 1:51.93a | NC | Southern Lee | CFVC Championship Meet | Thu, May 3 |
| 9. | - | | Relay Team | 1:52.20 | NC | J. F. Webb | Mid-State 3A Conference Championship | Tue, May 1 |
| 10. | - | | Janneca Williams
Angel Wilson
Derricka Zigler
Lisa Foster | 1:53.00 | NC | North Forsyth | Mid-Piedmont 3A Conference Championship | Tue, May 1 |
| 11. | - | | Relay Team | 1:53.30 | NC | Chapel Hill | Mid-State 3A Conference Championship | Tue, May 1 |
| 12. | - | | Relay Team | 1:53.35a | NC | Northern Guilford | NCHSAA 3A Regional Meet | Sat, May 12 |
| 13. | - | | Relay Team | 1:53.64a | NC | Eastern Guilford | NCHSAA 3A Regional Meet | Sat, May 12 |
| 14. | - | | Relay Team | 1:54.09a | NC | Western Harnett | Cape Fear Valley Championship Meet | Wed, May 2 |
| 15. | - | | Victoria Davis
Hannah Phillips
Rachael Breasseale
Jaden Roy | 1:54.63a | NC | Union Pines | Cape Fear Valley Championship Meet | Wed, May 2 |
| 16. | - | | Relay Team | 1:54.90a | NC | Overhills | CFVC Meet | Thu, Mar 22 |
| 17. | - | | Relay Team | 1:55.50 | NC | Orange | Mid-State 3A Conference Championship | Tue, May 1 |
| 18. | - | | Relay Team | 1:56.00 | NC | Southern Vance | Mid-State 3A Conference Championship | Tue, May 1 |
| 19. | - | | Relay Team | 1:56.40 | NC | Cardinal Gibbons | Mid-State 3A Conference Championship | Tue, May 1 |
| 20. | - | | Relay Team | 1:59.10 | NC | Ledford Senior | Mid-Piedmont 3A Conference Championship | Tue, May 1 |
| 21. | - | | Sierra Gatling
Emma Loutzenheiser
Lauren Freeman
Cali Pacheco | 2:03.20 | NC | Southwestern Randolph | Mid-Piedmont 3A Conference Championship | Tue, May 1 |
| 22. | - | | Relay Team | 2:11.50 | NC | Gray's Creek | Cape Fear Valley Meet I | Thu, Mar 8 |
