| 1. | - | | Relay Team | 3:49.73a | PA | Central Bucks West | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 2. | - | | Relay Team | 3:50.10a | PA | Pennsbury | PIAA State Championships | Sat, May 26 |
| 3. | - | | Relay Team | 3:50.14a | PA | Coatesville Area | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 4. | - | | Relay Team | 3:50.67a | PA | Strath Haven | PIAA State Championships | Sat, May 26 |
| 5. | - | | Relay Team | 3:53.46a | PA | Central Bucks South | PIAA State Championships | Fri, May 25 |
| 6. | - | | Relay Team | 3:54.07a | PA | Penn Wood | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 7. | - | | Relay Team | 3:54.59a | PA | Pennridge | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 8. | - | | Relay Team | 3:58.61a | PA | Upper Darby Senior | PIAA State Championships | Fri, May 25 |
| 9. | - | | Relay Team | 4:00.19a | PA | Upper Dublin | Abington Invitational | Fri, Apr 20 |
| 10. | - | | Relay Team | 4:00.91a | PA | Central Bucks East | SOL Continental Conference Championships | Sat, May 12 |
| 11. | - | | Relay Team | 4:01.01a | PA | Avon Grove | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 12. | - | | Relay Team | 4:01.04a | PA | Gwynedd Mercy | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 13. | - | | Relay Team | 4:01.47a | PA | Neshaminy | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 14. | - | | Relay Team | 4:01.85a | PA | Phoenixville Area | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 15. | - | | Relay Team | 4:02.64a | PA | Penncrest | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 16. | - | | Relay Team | 4:02.69a | PA | Lower Merion | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 17. | - | | Relay Team | 4:03.20a | PA | Spring Ford | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 18. | - | | Relay Team | 4:03.54a | PA | Council Rock South | SOL National Conference Championships | Sat, May 12 |
| 19. | - | | Relay Team | 4:03.94a | PA | Bensalem | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 20. | - | | Relay Team | 4:05.18a | PA | Cheltenham | SOL American Conference Championships | Sat, May 12 |
| 21. | - | | Relay Team | 4:05.25a | PA | Conestoga | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 22. | - | | Relay Team | 4:05.37a | PA | Upper Merion Area | SOL American Conference Championships | Sat, May 12 |
| 23. | - | | Relay Team | 4:05.59a | PA | Mt Saint Joseph Academy | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 24. | - | | Relay Team | 4:05.85a | PA | Boyertown Area | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 25. | - | | Relay Team | 4:05.93a | PA | Downingtown East | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 26. | - | | Relay Team | 4:06.65a | PA | Abington | Abington Invitational | Fri, Apr 20 |
| 27. | - | | Relay Team | 4:06.70a | PA | North Penn (Lansdale) | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 28. | - | | Relay Team | 4:06.99a | PA | Downingtown West | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 29. | - | | Relay Team | 4:07.20a | PA | Upper Perkiomen | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 30. | - | | Relay Team | 4:08.85a | PA | Haverford Twp. | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 31. | - | | Relay Team | 4:09.26a | PA | Souderton Area | SOL Continental Conference Championships | Sat, May 12 |
| 32. | - | | Relay Team | 4:09.60 | PA | Garnet Valley | Upper Darby Relays | Sat, Mar 24 |
| 33. | - | | Christina Mapa
Kim Lapczynaski
Hannah Weismen
Taylor Thames | 4:10.54a | PA | Unionville | Downingtown West Spring Invitational | Fri, Mar 30 |
| 34. | - | | Relay Team | 4:11.24a | PA | Villa Maria Academy (Girls) | PIAA State Championships | Fri, May 25 |
| 35. | - | | Relay Team | 4:11.29a | PA | Wissahickon | SOL American Conference Championships | Sat, May 12 |
| 36. | - | | Relay Team | 4:12.61a | PA | William Tennent | SOL National Conference Championships | Sat, May 12 |
| 37. | - | | Relay Team | 4:13.04a | PA | Quakertown Comm Senior | SOL Continental Conference Championships | Sat, May 12 |
| 38. | - | | Relay Team | 4:13.55a | PA | Methacton | PIAA District 1 AAA and AA Championships | Sat, May 19 |
| 39. | - | | Relay Team | 4:14.14a | PA | Plymouth-Whitemarsh | SOL American Conference Championships | Sat, May 12 |
| 40. | - | | Relay Team | 4:16.00a | PA | Council Rock North | SOL National Conference Championships | Sat, May 12 |
| 41. | - | | Relay Team | 4:16.78a | PA | Radnor | Plymouth Whitemarsh Colonial Relays | Sat, Apr 7 |
| 42. | - | | Relay Team | 4:17.92a | PA | Upper Moreland | SOL American Conference Championships | Sat, May 12 |
| 43. | - | | Devon Towell
Megan Barrett
Elizabeth Duguid
Lindsay Pratt | 4:18.76a | PA | West Chester East | Rustin Invitational | Wed, Apr 4 |
| 44. | - | | Relay Team | 4:18.94a | PA | Norristown Area | Plymouth Whitemarsh Colonial Relays | Sat, Apr 7 |
| 45. | - | | Relay Team | 4:21.62a | PA | Hatboro Horsham Senior | SOL Continental Conference Championships | Sat, May 12 |
| 46. | - | | Brittney Pospiech
Maura Lavelle
Alex Edger
Elena Silla | 4:28.01a | PA | Nazareth Academy Private | Rustin Invitational | Wed, Apr 4 |
| 47. | - | | Amber Hontz
Annie Pitts
Nora Powell
Emily Walls | 4:30.75a | PA | West Chester Rustin | Rustin Invitational | Wed, Apr 4 |
| 48. | - | | Aniya Gibbs
Meyadah Hill
Lajee Barnes
Liana Byrd | 4:33.00 | PA | Chester | Diamond State Relays | Sat, Mar 31 |
| 49. | - | | Relay Team | 4:37.20 | PA | Ridley | Upper Darby Relays | Sat, Mar 24 |
| 50. | - | | TyZhae Rothwell
Brittany Roberts
Sydni Jean
Brianna McKnight | 4:38.00 | PA | Chichester | Diamond State Relays | Sat, Mar 31 |
| 51. | - | | Relay Team | 4:40.80 | PA | Marple Newtown | Upper Darby Relays | Sat, Mar 24 |
| 52. | - | | Relay Team | 4:43.00 | PA | Springfield (Delco) | Upper Darby Relays | Sat, Mar 24 |
