| 1. | - | | Annie Callegary
Sarah Allen
Megan Doyle
Emily Porter | 1:45.24a | TX | St Michaels Catholic | TAPPS 5A State Championship | Sat, May 5 |
| 2. | - | | Claire Williams
Gabrielle Howard
Roxana Hernandez
Cori Steele | 1:46.24a | TX | Bishop Lynch | TAPPS 5A State Championship | Sat, May 5 |
| 3. | - | | Chelsea Classo
Amber Moore
Gabrielle Puente
Gwenyth Puente | 1:46.89a | TX | Nolan Catholic | TAPPS 5A State Championship | Sat, May 5 |
| 4. | - | | Madison Sheehy
Kelsey Crawford
Morgann Davis
Taylor Crawford | 1:47.50 | TX | Houston Christian | Cypress Springs Meet | Thu, Mar 8 |
| 5. | - | | Katherine Allen
Courtney Williams
Dominique Hever
Chrissy Madsen | 1:47.72a | TX | Ursuline Academy | TAPPS Track and Field State Meet | Fri, May 4 |
| 6. | - | | Erin White
Razan Beidas
Bridget Daly
Jackie Manley | 1:48.24a | TX | Duchesne Academy | TAPPS 5A State Championship | Sat, May 5 |
| 7. | - | | Anna Altinger
Chloe Harrison
Alex Guidry
Brooke Sullivan | 1:50.01a | TX | St Agnes Academy | TAPPS 5A Houston District Meet | Thu, Apr 12 |
| 8. | - | | Rachel Dingler
Molly Coward
Sydney Hicks
Kelsey Saldivar | 1:50.66a | TX | Prestonwood Christian | TAPPS 1-5A District Meet | Thu, Apr 12 |
| 9. | - | | Jasmine Acosta
Jasmine L Blair
Rachel Frei
Sarah K Jeffreys | 1:50.74a | TX | Antonian College Prep | TAPPS 5A State Championship | Sat, May 5 |
| 10. | - | | Karoline Fields
Mary Braley
Peyton Travis
Tylre Roberson | 1:51.78a | TX | Trinity Christian (Addison) | Tom Landry Relays - HS | Fri, Mar 30 |
| 11. | - | | Natalia De la garza
Daniela Fuentes
Marissa Gomez
Megan Retana | 1:52.78a | TX | St Joseph Academy | TAPPS 5A State Championship | Sat, May 5 |
| 12. | - | | Mackenzie Millican
Brooke Alexander
Hanna Elsey
Paige Jeary | 1:53.27a | TX | Liberty Christian | TAPPS 1-5A District Meet | Thu, Apr 12 |
| 13. | - | | Taylor Gillespie
Ariana Montelongo
LaMiracle Ledet
Gabby Montalvo | 1:55.98a | TX | Incarnate Word Academy | EHS Relays, Day 2 - Running Events Only | Sat, Feb 25 |
| 14. | - | | Jacqueline Jones
Katie Schumacher
Tess Gilboux
Helene Weideman | 1:57.32a | TX | John Paul II | Tom Landry Relays - HS | Fri, Mar 30 |
| 15. | - | | Jordan Powell
Asia Woods
Victoria Chavez
Kendall Chancellor | 1:57.98a | TX | St Pius X | CCS Relays | Thu, Apr 5 |
