| 1. | - | | Nikki Ashbaugh
Destiny Harrison
Devyn Hosby
Rhonda Rogombe | 4:04.57a | WV | Washington | WVSSAC State Track & Field Championship Two-Day Meet | Sat, May 19 |
| 2. | - | | Emily Godwin
Lauren Cvechko
Karli Littler
Abby Lantz | 4:15.64a | WV | Buckhannon-Upshur | Bridgeport CVB Invitational | Sat, Mar 24 |
| 3. | - | | Desiree McCarroll
Selena Renteria
Maria Russo
Bryanna Doughty | 4:16.76a | WV | Jefferson | WVSSAC State Track & Field Championship Two-Day Meet | Sat, May 19 |
| 4. | - | | Morganne Phillips
Lindsey Deberry
Jenna Alonge
Anna-Kay Haddix | 4:16.87a | WV | Bridgeport | WVSSAC State Track & Field Championship Two-Day Meet | Sat, May 19 |
| 5. | - | | Anna Lizon
Megan Breen
Lexi Beach
Fallon Stone | 4:24.16a | WV | Hedgesville | WVSSAC Region II AAA | Thu, May 10 |
| 6. | - | | Nichole Henderson
Madelyn Trucks
Heather Jenkins
Jessica McCarty | 4:24.89a | WV | Musselman | WVSSAC Region II AAA | Thu, May 10 |
| 7. | - | | Jenna Westfall
Taylor Harwood
Rebekah Lewis
Sarah Burkett | 4:25.20 | WV | Hampshire | AMAC Championship | Wed, Apr 25 |
| 8. | - | | Essence Underwood
Jasmine Barksdale
Megan Martin
Megan Herdering | 4:36.91a | WV | Martinsburg | PVC Conference Championship | Sat, May 5 |
| 9. | - | | Kathlyne Simmons
Isabella Nieves
Elise Reed
Tennyson DeMarco | 4:38.04a | WV | Elkins | WVSSAC Region II AAA | Thu, May 10 |
| 10. | - | | Jessica Hefner
Janine Posey
Cheyenne Corathers
Josie Kemper | 4:50.98a | WV | Lewis County | WVSSAC Region II AAA | Thu, May 10 |
| 11. | - | | Samantha Buffey
Catherine Fox
Victoria Carvelli
Hannah Lemasters | 5:08.11a | WV | Robert C Byrd | Buckhannon-Upshur Track Meet I | Tue, Mar 20 |
