| 1. | 11 | | Samantha Michell | 42.23a | MI | Reed City | MHSAA Division 3 State Final | Sat, Jun 2 |
| 2. | 12 | | Cindy Ofili | 43.53a | MI | Ann Arbor Huron | Midwest Meet of Champions | Sat, Jun 9 |
| 3. | 12 | | Laticia Sims | 44.59a | MI | Farmington Hills Harrison | Oakland County Championship | Fri, May 25 |
| 4. | 12 | | Emily Wee | 45.01a | MI | Frankenmuth | MHSAA Division 3 State Final | Sat, Jun 2 |
| 5. | 12 | | Sophia Kunselman | 45.05a | MI | Ann Arbor Pioneer | MHSAA Region 3-1 | Fri, May 18 |
| 6. | 11 | | Samantha Zakalowski | 45.24c | MI | Algonac | MHSAA Region 20-2 | Fri, May 18 |
| 7. | 12 | | Tori Desira | 45.25a | MI | DeWitt | MHSAA Div. II State Finals | Sat, Jun 2 |
| 8. | 11 | | Sarah Moen | 45.54c | MI | St. Clair Shores Lakeview | Mustang Invitational | Fri, May 11 |
| 9. | 11 | | Aaron Howell | 45.57a | MI | Farmington | MHSAA Region 6-1 | Sat, May 19 |
| 10. | 12 | | Lameeka Davis | 45.61a | MI | East Kentwood | OK Red Conference Finals | Fri, May 11 |
| 11. | 12 | | Elizabeth Dutcher | 45.66a | MI | Williamston | CAAC WHITE: Lansing Catholic vs. Williamston | Tue, May 15 |
| 12. | 10 | | Chinonye Uche | 45.67a | MI | Ann Arbor Pioneer | MHSAA LP D1 State Track and Field Final | Sat, Jun 2 |
| 13. | 11 | | Paige Wells | 45.90a | MI | Allendale | MHSAA Div. II State Finals | Sat, Jun 2 |
| 14. | 10 | | Ashlynn Schiro | 45.91a | MI | Okemos | Alma College Scottie Classic | Sat, May 12 |
| 15. | 10 | | Madison Arnouts | 46.01a | MI | Grand Ledge | MHSAA LP D1 State Track and Field Final | Sat, Jun 2 |
| 16. | 10 | | Savanah Feldpausch | 46.04c | MI | Fowler | CMAC @ Bath | Tue, May 15 |
| 10 | | Breanna Luba | 46.04c | MI | Southgate Anderson | DRL Championship | Tue, May 22 |
| 18. | 12 | | Rebecca Quaintance | 46.14c | MI | Walled Lake Northern | MHSAA Regionals | Fri, May 18 |
| 12 | | Becca Quaintance | 46.14c | MI | Walled Lake Northern | MHSAA Regionals | Fri, May 18 |
| 20. | 11 | | Paige Anderson | 46.22a | MI | Berrien Springs | MHSAA Regional 11-2 at Vicksburg | Fri, May 18 |
| 21. | 12 | | Taylor Tepper | 46.23a | MI | Grandville | OK Red Conference Finals | Fri, May 11 |
| 22. | 11 | | Mallory Myler | 46.24c | MI | Dearborn Divine Child | Dearborn All-Area Championship | Fri, May 11 |
| 12 | | Kelly McCloskey | 46.24c | MI | Novi | KLAA Championships | Tue, May 22 |
| 24. | 10 | | Kylie Hicks | 46.30a | MI | Boyne City | MHSAA Region 30 | Sat, May 19 |
| 25. | 12 | | Samantha Rajewski | 46.34c | MI | Petoskey | MHSAA Region 19-2 at Chippewa Hills | Fri, May 18 |
| 26. | 12 | | Sabrina Kunselman | 46.40a | MI | Ann Arbor Pioneer | MHSAA Region 3-1 | Fri, May 18 |
| 12 | | Jennifer Jarema | 46.40a | MI | Midland | SVL Championship | Wed, May 23 |
| 28. | 10 | | Anna Haritos | 46.43a | MI | Auburn Hills Avondale | MHSAA Div. II State Finals | Sat, Jun 2 |
| 29. | 10 | | Ce'Aira Richardson | 46.44c | MI | Bridgeport | Korf/Schultz Saginaw County Meet | Tue, May 29 |
| 30. | 11 | | Kirsten Smith | 46.45a | MI | Westland John Glenn | KLAA-Kensington Conference Meet | Fri, May 11 |
| 31. | 12 | | Candace Krause | 46.49a | MI | Benton Harbor | MHSAA Div. II State Finals | Sat, Jun 2 |
| 32. | 12 | | Addy Kleinhardt | 46.54a | MI | Clare | MHSAA Region 27-3 @ Mason County Central | Fri, May 18 |
| 9 | | Gabrielle Collins | 46.54c | MI | Caro | TVC-East | Wed, May 23 |
| 34. | 12 | | Bethany Easom | 46.64a | MI | Saline | Saline vs. Huron | Tue, May 1 |
| 12 | | Sidney Bischer | 46.64c | MI | Yale | MHSAA Region 20-2 | Fri, May 18 |
| 10 | | Heather Johnson | 46.64c | MI | Rochester Adams | MHSAA Division 1 Regional #9 | Fri, May 18 |
| 37. | 12 | | Rosanna Reynolds | 46.70a | MI | Dearborn Divine Child | MHSAA 13-2 Regional @ Livonia Ladywood | Fri, May 18 |
| 38. | 12 | | Paige Stepanski | 46.74c | MI | Alpena | Big North Conference Championship | Wed, May 23 |
| 39. | 11 | | Anna Newhof | 46.77a | MI | Grand Rapids South Christian | OK Gold Conference Championship Meet | Sat, May 12 |
| 40. | 9 | | Lauren Rodriguez | 46.84c | MI | Northville | MHSAA Regionals | Fri, May 18 |
| 41. | 10 | | Destiny Fortune | 46.85a | MI | Brownstown Woodhaven | MHSAA Region 3-1 | Fri, May 18 |
| 42. | 11 | | Luke Hayter | 46.94c | MI | Dexter | Dexter vs. Adrian | Tue, Apr 10 |
| 43. | 11 | | Molly Jarvis | 47.03a | MI | Livonia Churchill | KLAA-Kensington Conference Meet | Fri, May 11 |
| 11 | | Rosalyn Wyse | 47.03a | MI | Greenville | MHSAA Regionals 1-1 | Sat, May 19 |
| 45. | 11 | | Natalie Peterson | 47.04c | MI | Romeo | Macomb County Meet | Thu, May 24 |
| 46. | 12 | | Kelsey Butcher | 47.09a | MI | Morrice | GAC League meet | Tue, May 15 |
| 47. | 10 | | Kristen Higgins | 47.14c | MI | Portage Northern | Portage Northern vs. St. Joseph | Tue, May 8 |
| 7 | | Paige Anderson | 47.14c | MI | Berrien Springs | Allegan Invitational | Fri, May 11 |
| 49. | 11 | | Allie Gast | 47.15a | MI | Grandville | MHSAA Regionals 1-1 | Sat, May 19 |
| 50. | 9 | | Kayla Gandy | 47.19a | MI | Dearborn Divine Child | MHSAA Div. II State Finals | Sat, Jun 2 |
| 51. | 11 | | Lina Davis | 47.22a | MI | Novi | MHSAA Region 6-1 | Sat, May 19 |
| 52. | 11 | | Sydney Tucker | 47.24c | MI | Walled Lake Central | Walled Lake Central @ Lakeland | Tue, Apr 10 |
| 11 | | Christina Micale | 47.24c | MI | Macomb Dakota | Macomb County Meet | Thu, May 24 |
| 54. | 12 | | Dillan Smith | 47.31a | MI | St. Joseph | MHSAA Div. II State Finals | Sat, Jun 2 |
| 55. | 11 | | Brooke Bovee | 47.32a | MI | Morenci | Daily Telegram Individual Invitational | Tue, May 29 |
| 56. | 12 | | Ashley Koprin | 47.34c | MI | St. Clair Shores Lakeview | MHSAA Regional @ GPS Region 5 | Fri, May 18 |
| 12 | | Emily Leppek | 47.34c | MI | Rochester | MHSAA Division 1 Regional #9 | Fri, May 18 |
| 58. | 10 | | Alison Rich | 47.42a | MI | Haslett | MHSAA Div. II State Finals | Sat, Jun 2 |
| 59. | 11 | | Christy Schultz | 47.51a | MI | Muskegon Reeths-Puffer | OK Black Finals | Thu, May 10 |
| 60. | 12 | | Emily Schaefer | 47.55a | MI | Grand Ledge | MHSAA Regional No. 2-1 Holt | Fri, May 18 |
| 10 | | Angela Ciaravino | 47.55a | MI | Lapeer East | MHSAA Div. II State Finals | Sat, Jun 2 |
| 62. | 11 | | Hannah Shellenbarger | 47.60a | MI | Perry | CAAC WHITE: League Championships | Wed, May 23 |
| 63. | 12 | | Amanda Glass | 47.62a | MI | Byron | MHSAA Regional 25-3 at Bath | Fri, May 18 |
| 64. | 12 | | Melissa Vu | 47.63a | MI | Jenison | OK Red Conference Finals | Fri, May 11 |
| 65. | 12 | | Jessica Beeler | 47.64c | MI | Holly | MHSAA Division 1 Regional #9 | Fri, May 18 |
| 66. | 10 | | Olivia Llewelyn | 47.67a | MI | Saginaw Heritage | SVL Championship | Wed, May 23 |
| 67. | 12 | | Sylvia Maxwell | 47.72a | MI | Lansing Waverly | MHSAA Div. II State Finals | Sat, Jun 2 |
| 68. | 10 | | Kathryn Schmidt | 47.74c | MI | Hartland | MHSAA Regionals | Fri, May 18 |
| 10 | | Jennie Styf | 47.74c | MI | Hamilton | Allegan News County Invite | Wed, May 30 |
| 70. | 11 | | Drew Findlay | 47.90a | MI | Reese | MHSAA Division 3, Region 29-3 | Sat, May 19 |
| 71. | 11 | | Natalie Wysocki | 47.91a | MI | Saline | JD's Invitational | Fri, Apr 27 |
| 72. | 10 | | Karrington Seals | 47.93a | MI | Farmington Hills North Farmington | Oakland County Championship | Fri, May 25 |
| 73. | 11 | | Audrey Wyse | 48.01a | MI | Greenville | OK White Conference Meet - Finals | Fri, May 11 |
| 74. | 11 | | Sydney Tucker | 48.04c | MI | Walled Lake Central | MHSAA Regionals | Fri, May 18 |
| 75. | 11 | | Brianna Greinke | 48.05a | MI | Muskegon Reeths-Puffer | 34th Annual Meijer West Michigan Invitational | Thu, May 24 |
| 76. | 11 | | Nikki Redman | 48.07a | MI | Hastings | MHSAA Div. II State Finals | Sat, Jun 2 |
| 77. | 10 | | Hannah Reynard | 48.10a | MI | Napoleon | MHSAA Division 3 State Final | Sat, Jun 2 |
| 78. | 12 | | Bria Williams | 48.12a | MI | Ypsilanti Lincoln | SEC Girls Championships | Wed, May 23 |
| 12 | | Mikele Drummond | 48.12a | MI | Ravenna | 34th Annual Meijer West Michigan Invitational | Thu, May 24 |
| 80. | 12 | | Corinne Roller | 48.23a | MI | Richland Gull Lake | SMAC Division Meet | Fri, May 11 |
| 11 | | Natalie Puckett | 48.23a | MI | Plymouth | MHSAA Division 1, Regional 4 | Fri, May 18 |
| 82. | 12 | | Megan Carlson | 48.24c | MI | Gaylord | MHSAA Region 19-2 at Chippewa Hills | Fri, May 18 |
| 83. | 12 | | Kasey Blank | 48.26a | MI | Forest Hills Eastern | EGR Pioneer Classic Invite | Sat, May 5 |
| 84. | 9 | | Sydney Bronner | 48.28a | MI | Frankenmuth | MHSAA Division 3, Region 29-3 | Sat, May 19 |
| 85. | 9 | | J'Laan Pittman | 48.32a | MI | Beverly Hills Wylie E Groves | MHSAA Region 6-1 | Sat, May 19 |
| 12 | | Sam Rajewski | 48.32a | MI | Petoskey | MHSAA Div. II State Finals | Sat, Jun 2 |
| 87. | 10 | | Michelle Davis | 48.34c | MI | Reading | Ralph Crume Invitational | Sat, Apr 21 |
| 88. | 11 | | Emily Prins | 48.35a | MI | Grand Rapids Catholic Central | EGR Pioneer Classic Invite | Sat, May 5 |
| 89. | 9 | | Jessica Gustad | 48.38a | MI | Manistee | MHSAA Region 27-3 @ Mason County Central | Fri, May 18 |
| 90. | 11 | | Emily Wilburn | 48.43a | MI | Rockford | OK Red Conference Finals | Fri, May 11 |
| 91. | 9 | | Allison Hufnagel | 48.44c | MI | Fowler | CMAC @ Bath | Tue, May 15 |
| 9 | | Quinn Hall | 48.44c | MI | Traverse City West | MHSAA Region 10-1 at Bay City Western | Fri, May 18 |
| 11 | | Fredrika Russell | 48.44c | MI | Flushing | MHSAA Region 10-1 at Bay City Western | Fri, May 18 |
| 94. | 10 | | Franzi Loetzner | 48.49a | MI | Clarkston | Golden Triangle Invitational | Fri, May 4 |
| 95. | 9 | | Jennifer Davis | 48.54c | MI | Reading | Union City v Reading | Thu, Apr 19 |
| 11 | | Krista Kinsey | 48.54a | MI | Bath | MHSAA Regional 25-3 at Bath | Fri, May 18 |
| 10 | | Kayla Richmond | 48.54c | MI | Chesaning | Korf/Schultz Saginaw County Meet | Tue, May 29 |
| 98. | 12 | | Libby Schichtel | 48.55a | MI | Grand Rapids West Catholic | OK Blue Conference Finals | Fri, May 11 |
| 99. | 10 | | Danielle Howard | 48.56a | MI | Ann Arbor Huron | Golden Triangle Invitational | Fri, May 4 |
| 100. | 12 | | Kally Verkaik | 48.60a | MI | Holland Christian | MHSAA Div. II State Finals | Sat, Jun 2 |
| 101. | 12 | | Daeja Raglin | 48.63a | MI | Ypsilanti | Siena Heights Invitational | Fri, May 11 |
| 12 | | Teanne Townsend | 48.63a | MI | Brownstown Woodhaven | News-Herald Championships | Sat, May 12 |
| 103. | 10 | | Mackenzie Micho | 48.72a | MI | East Grand Rapids | OK White Conference Meet - Finals | Fri, May 11 |
| 10 | | Quenee' Dale | 48.72a | MI | Saline | MHSAA Region 3-1 | Fri, May 18 |
| 105. | 12 | | Andrea Polley | 48.74c | MI | Delton-Kellogg | Allegan Invitational | Fri, May 11 |
| 12 | | Jen Lentz | 48.74c | MI | Standish Sterling | MHSAA Region 19-2 at Chippewa Hills | Fri, May 18 |
| 11 | | Anna Spotts | 48.74c | MI | Hamilton | Allegan News County Invite | Wed, May 30 |
| 108. | 11 | | Brooke Colville | 48.75a | MI | Harrison Community | MHSAA Region 27-3 @ Mason County Central | Fri, May 18 |
| 12 | | Asia Jones | 48.75a | MI | Lansing Sexton | CAAC Blue Division | Wed, May 23 |
| 110. | 12 | | Celestine Schwartz | 48.79a | MI | Paw Paw | MITCA Division 2 Team State Championship | Sat, May 26 |
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(Total stats: 1,422)
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