| 1. | - | Alex Isom
Briana Wilson
Vivianna Carter
Peyton Chaney | 50.81a | Nerinx Hall | |
| 2. | - | Pam Ekpelu
Julia Olson
Kate Pflager
Cameron Jackson | 51.00a | Mary Institute-Count... | |
| 3. | - | Josselyn Adams
Suaddah Irvin-Muhammad
Aiesha Irvin-Muhammad
Lauren Person | 51.14a | St Elizabeth Academy | |
| 4. | - | Lea Johnson
Hannah Heard
Sandra Yamada
Tiffani Ferrell | 51.32a | John Burroughs | |
| 5. | - | Jasmine Cawley
Dana Kaempfe
KiNikki King
Lauren Dalton | 51.53a | Lutheran South | |
| 6. | - | Brittany Ross
Mikaila Peery
Josilyn McGee-Smith
Nyeshia Melton | 51.99a | Lutheran North | |
| 7. | - | Claire Anglo
Katie Grunik
Caitlin Shukwit
Caitlyn Slattery | 52.26a | Cor Jesu Academy | |
| 8. | - | Hien Nguyen
Kelsey Lee
Alatra Wansley
Angela Reynolds | 53.61a | Desoto | |
| 9. | - | Brown Bria
Katie Driskill
Mar'Quel Collins
Alexandria Stith | 53.68a | Trinity Catholic | |
| 10. | - | Kristen Macke
Jamie Varghese
Ashley Hupfeld
Andrea Hessler | 53.95a | Ursuline Academy | |
| 11. | - | Gabby Thompson
Nicole Saville
Kendra Hercules
Megan Bucol | 54.23a | Villa Duchesne | |
| 12. | - | Kayla Hampton
Maggie Kane
Lauren Vanek
Julia Wiens | 54.97a | Westminster Christian | |
| 13. | - | Molly Soto
Rachel Volmert
Madeline Gilstrap
Kim Theis | 55.16a | St Josephs Academy | |
| 14. | - | Ranjana Kodwani
Claire Borst
Pauli Hampel
Meghan Faddis | 56.22a | Visitation Academy | |
| 1. | - | Julia Olson
Cameron Jackson
CeCe Moore
Lauren Waterbury | 1:44.53a | Mary Institute-Count... | |
| 2. | - | Taylor Porter
Hali Ford
Shawna Carmack
Cheyenne Hoerr | 1:47.50a | Affton | |
| 3. | - | Josselyn Adams
Suaddah Irvin-Muhammad
Aiesha Irvin-Muhammad
Lauren Person | 1:49.03a | St Elizabeth Academy | |
| 4. | - | Kelsey Lee
Deanna Peters
Abby Reynolds
Alatra Wansley | 1:50.68a | Desoto | |
| 5. | - | Jasmine Cawley
Lauren Dalton
Dana Kaempfe
Taylor Kirchwehm | 1:51.16a | Lutheran South | |
| 6. | - | Josilyn McGee-Smith
Nyeshia Melton
Amber Rogers
Mikaila Peery | 1:51.59a | Lutheran North | |
| 7. | - | Claire Anglo
Christie Lewis
Kaitlin McAlexander
Mary Hapak | 1:53.15a | Cor Jesu Academy | |
| 8. | - | Brown Bria
Katie Driskill
Torshe Triplett
Alexandria Stith | 1:53.23a | Trinity Catholic | |
| 9. | - | Sandra Yamada
Tiffani Ferrell
Miriam Cruz
Hannah Heard | 1:53.53a | John Burroughs | |
| 10. | - | Gabby Thompson
Nicole Saville
Annie Price
Kendra Hercules | 1:53.64a | Villa Duchesne | |
| 11. | - | Relay Team | 1:55.24a | Notre Dame (Saint Lo... | |
| 12. | - | Jamie Varghese
Meg Vatterott
Meg Brady
Andrea Hessler | 1:55.33a | Ursuline Academy | |
| 13. | - | Jamie Potter
Megan Hennon
Anna Marchiony
Lauren Brandon | 2:02.46a | St Josephs Academy | |
| 14. | - | Elizabeth Lovinggood
Catherine Hagedorn
Lauren Eggert
Anna Schwartz | 2:05.98a | Visitation Academy | |
| -- | - | Relay Team | DQ | Nerinx Hall | |
| 1. | - | Julia Olson
Madison Mann
Heather Cousins
CeCe Moore | 4:07.60a | Mary Institute-Count... | |
| 2. | - | Jill Whitman
Shelby Nord
Kaitlin McAlexander
Katie Sainz | 4:13.32a | Cor Jesu Academy | |
| 3. | - | Lauren Dalton
Dana Kaempfe
Taylor Kirchwehm
Amanda Behnke | 4:15.85a | Lutheran South | |
| 4. | - | Kaitlyn Emig
Sarah Ross
Megan Campbell
Gabby Hantak | 4:16.82a | Rosati-Kain | |
| 5. | - | Riann Colbert
Nicole Saville
Megan Murphy
Annie Price | 4:19.49a | Villa Duchesne | |
| 6. | - | Jamie Varghese
Meg Brady
Meg Vatterott
Caitlyn Carroll | 4:21.37a | Ursuline Academy | |
| 7. | - | Lucy May
Jamie Potter
Hayley Wright
Susie Schmank | 4:37.13a | St Josephs Academy | |
| 8. | - | Brittany Ross
Zaria Weeden
Kamilah Jones
Amber Stout | 4:41.54a | Lutheran North | |
| 9. | - | Veronica Villhard
Gabbrielle Sewester
Marlee Friedman
Gabby Reppell | 4:47.60a | Notre Dame (Saint Lo... | |
| 10. | - | Christina Lam
Faith Andrews
Colleen Dulle
Emma Diller | 4:51.90a | Visitation Academy | |
| -- | - | Miriam Cruz
Alicia Liu
Rebecca McDonald
Sandra Yamada | DQ | John Burroughs | |
| -- | - | Deanna Peters
Angela Reynolds
Abby Reynolds
Claira Rhodes | DQ | Desoto | |
| 1. | - | Claire Minnick
Madeline Nathe
Katie Anderson
Carly Kraska | 9:58.63a | Nerinx Hall | |
| 2. | - | Elise Viox
Elise Ott
Jill Whitman
Sofia Cygnarowicz | 10:08.65a | Cor Jesu Academy | |
| 3. | - | Ramya Gruneisen
Adrienne Kaup
Courtney Powell
Dani Roberts | 10:10.52a | Westminster Christian | |
| 4. | - | Becca Hairer
Kathy McCormack
Shawna Carmack
Cheyenne Hoerr | 10:13.46a | Affton | |
| 5. | - | Riann Colbert
Lucy Sheahan
Anna Wattles
Cece Stock | 10:24.93a | Villa Duchesne | |
| 6. | - | Alicia Liu
Anna Stillman
Amanda Robiolio
Annalise Wagner | 10:33.13a | John Burroughs | |
| 7. | - | Relay Team | 10:37.65a | Ursuline Academy | |
| 8. | - | Sarah Ross
Sami Hantak
Alex Holzum
Gabby Hantak | 10:42.39a | Rosati-Kain | |
| 9. | - | Ashley Rubin
Emily Hunter
Holly Lanham
Caitlin McCartney | 10:56.88a | Visitation Academy | |
| 10. | - | Nicole Wieprecht
Emma Barden
Kate Landmann
Abbey Combest | 11:02.86a | St Josephs Academy | |
