| 1. | | Relay Team | 42.01a | - | MS | McComb | Southern Mississippi HS Invitational | Sat, Mar 7 |
| 2. | | Relay Team | 42.33a | - | MS | Vicksburg | MHSAA 4A State Championships | Fri, May 8 |
| 3. | | Sanquez Golson
Mitchell Keeton
Marcus Peairs
Martez Thompson | 42.34a | - | MS | Pascagoula | 5A South State | Sat, May 2 |
| 4. | | Jason Banks
Joe Price
Tamarco Taylor
Tobias Singleton | 42.35a | - | MS | Madison Central | 5A North State | Sat, May 2 |
| 5. | | Relay Team | 42.39a | - | MS | Southaven | MHSAA 5A State Championships | Sat, May 9 |
| 6. | | Relay Team | 42.50a | - | MS | Hernando | MHSAA 4A State Championships | Fri, May 8 |
| 7. | | Gabriel Campbell
Jeremy Davis
Rico Richardson
Travis Woods | 42.66a | - | MS | Natchez | 5A South State | Sat, May 2 |
| 8. | | Relay Team | 42.67a | - | MS | Terry | MHSAA 5A State Championships | Sat, May 9 |
| 9. | | Rickey Bradley
Albert Clark
Ivan Gray
Jay Hughes | 42.76a | - | MS | Oak Grove | MHSAA 5A State Championships | Sat, May 9 |
| 10. | | Relay Team | 42.95a | - | MS | Oxford | MHSAA 4A State Championships | Fri, May 8 |
| | Rashad Black
Charles Mays
Cedric Tillman
Kavarius Parker | 42.95a | - | MS | Grenada | 5A North State | Sat, May 2 |
| 12. | | Chad Bumphis
Justin Bean
Rich Heyer
Matt Mcintosh | 43.00a | - | MS | Tupelo | 5A North State | Sat, May 2 |
| 13. | | Relay Team | 43.09a | - | MS | Perry Central | MHSAA 3A State Championships | Fri, May 8 |
| 14. | | Relay Team | 43.10a | - | MS | Moss Point | MHSAA 4A State Championships | Fri, May 8 |
| 15. | | Relay Team | 43.11a | - | MS | Carthage | MHSAA 3A State Championships | Fri, May 8 |
| 16. | | Relay Team | 43.21a | - | MS | Gulfport | 5A South State | Sat, May 2 |
| 17. | | Lavon Brewster
Shaquille Fluker
Robert Handley
Joshua Hunter | 43.22a | - | MS | Meridian | 5A South State | Sat, May 2 |
| 18. | | Relay Team | 43.23a | - | MS | Holly Spring | MHSAA 3A State Championships | Fri, May 8 |
| 19. | | Relay Team | 43.34c | - | MS | Columbus | East Mississippi Classic | Thu, Apr 9 |
| 20. | | Relay Team | 43.45a | - | MS | Provine | 5A North State | Sat, May 2 |
| 21. | | Relay Team | 43.59a | - | MS | Newton County | MHSAA 3A State Championships | Fri, May 8 |
| 22. | | Relay Team | 43.62a | - | MS | Pearl | 4A North State | Mon, May 4 |
| 23. | | Relay Team | 43.64c | - | MS | Lafayette | Oxford HS Invitational | Sat, Mar 7 |
| 24. | | Relay Team | 43.75a | - | MS | Northeast Lauderdale | MHSAA 4A State Championships | Fri, May 8 |
| | Nick Brassell
Deshaun Henderson
Al Hentz
Xavier Lee | 43.75a | - | MS | South Panola | 5A North State | Sat, May 2 |
| 26. | | Relay Team | 43.85a | - | MS | Leflore County | MHSAA 2A State Championships | Sat, May 9 |
| 27. | | Relay Team | 43.93a | - | MS | Picayune Memorial | Southern Mississippi HS Invitational | Sat, Mar 7 |
| 28. | | Relay Team | 43.94a | - | MS | J Z George | MHSAA 2A State Championships | Sat, May 9 |
| 29. | | Relay Team | 43.95a | - | MS | Amanda Elzy | MHSAA 3A State Championships | Fri, May 8 |
| 30. | | Relay Team | 43.97a | - | MS | Forest Hill | MHSAA 4A State Championships | Fri, May 8 |
| 31. | | Relay Team | 43.99a | - | MS | Harrison Central | Southern Mississippi HS Invitational | Sat, Mar 7 |
| 32. | | Kempton Pritchard
Kolby McFarland
Kadero Edley
John Chase | 44.03a | - | MS | Raymond | Southern Mississippi HS Invitational | Sat, Mar 7 |
| 33. | | Relay Team | 44.09a | - | MS | Bay Senior | MHSAA 4A State Championships | Fri, May 8 |
| 34. | | Scott Austin
Tyrone Baker
Julius Harris
Geovanni Heron | 44.18a | - | MS | Biloxi | 5A South State | Sat, May 2 |
| 35. | | Terrel Ivy
Ruben Duckworth
Donavon Belle
Malcolm Hathorn | 44.36a | - | MS | Mt Olive | MHSAA 1A State Championships | Sat, May 9 |
| 36. | | Relay Team | 44.44c | - | MS | Pontotoc | Oxford HS Invitational | Sat, Mar 7 |
| 37. | | Relay Team | 44.52a | - | MS | Bruce | MHSAA 2A State Championships | Sat, May 9 |
| 38. | | Edrick Booth
Larry Copeland
Josh Griffith
Jeremy Johnson | 44.59a | - | MS | Bassfield | MHSAA 2A State Championships | Sat, May 9 |
| 39. | | Relay Team | 44.61a | - | MS | Clinton | Southern Mississippi HS Invitational | Sat, Mar 7 |
| 40. | | Relay Team | 44.65a | - | MS | Drew | MHSAA 1A State Championships | Sat, May 9 |
| 41. | | Relay Team | 44.73a | - | MS | Franklin County | Southern Mississippi HS Invitational | Sat, Mar 7 |
| 42. | | Creighton Serrette
Darrel Smith
Martrez Townes
Ron Watson | 44.74c | - | MS | Desoto Central | Oxford HS Invitational | Sat, Mar 7 |
| 43. | | Relay Team | 44.81a | - | MS | Broad Street | MHSAA 1A State Championships | Sat, May 9 |
| 44. | | Relay Team | 45.07a | - | MS | St Patrick | MHSAA 2A State Championships | Sat, May 9 |
| 45. | | Relay Team | 45.22a | - | MS | Newton | MHSAA 2A State Championships | Sat, May 9 |
| | Relay Team | 45.22a | - | MS | Lanier | 4A North State | Mon, May 4 |
| 47. | | Relay Team | 45.30a | - | MS | Charleston | MHSAA 3A State Championships | Fri, May 8 |
| 48. | | Relay Team | 45.31a | - | MS | Pisgah | MHSAA 1A State Championships | Sat, May 9 |
| 49. | | Relay Team | 45.44c | - | MS | Bay Springs | East Mississippi Classic | Thu, Apr 9 |
| 50. | | Desmon Hayes
Najee Lamar
Obrien Stewart
Jeremy Young | 45.54c | - | MS | Saltillo | Oxford HS Invitational | Sat, Mar 7 |
| 51. | | Kasey Akins
Troy Taylor
Pete West
Billy Shed | 45.64a | - | MS | Starkville | Southern Mississippi HS Invitational | Sat, Mar 7 |
| 52. | | Relay Team | 45.74c | - | MS | North Panola | Oxford HS Invitational | Sat, Mar 7 |
| | Relay Team | 45.74c | - | MS | Noxubee County | East Mississippi Classic | Thu, Apr 9 |
| | Relay Team | 45.74c | - | MS | Laurel | East Mississippi Classic | Thu, Apr 9 |
| 55. | | Relay Team | 45.75a | - | MS | Coldwater | MHSAA 1A State Championships | Sat, May 9 |
| 56. | | Relay Team | 45.76a | - | MS | St Andrews Episcopal | Southern Mississippi HS Invitational | Sat, Mar 7 |
| | Relay Team | 45.76a | - | MS | West Bolivar District | MHSAA 2A State Championships | Sat, May 9 |
| 58. | | Antonio Coleman
Dearius Blanton
Tim Jones
Patrick Taylor | 45.84a | - | MS | Warren Central | Southern Mississippi HS Invitational | Sat, Mar 7 |
| | Carnell Gray
Oscar Heidelberg
Adrian Moore
Deanthony Pickens | 45.84c | - | MS | Quitman County | East Mississippi Classic | Thu, Apr 9 |
| 60. | | Carlton Coleman
Dequinton Dean
Drexter Dotson
Devontay Jones | 45.94c | - | MS | West Jones | Meridian HS Invitational | Sat, Mar 28 |
| 61. | | Relay Team | 46.04c | - | MS | Kossuth | Oxford HS Invitational | Sat, Mar 7 |
| 62. | | Michael Bonner
Matthew Johnson
Greg Jones
Demetrius Plummer | 46.34c | - | MS | Northeast Jones | East Mississippi Classic | Thu, Apr 9 |
| 63. | | Relay Team | 46.36a | - | MS | Aberdeen | MHSAA 3A State Championships | Fri, May 8 |
| 64. | | Marcus Brooks
Dejuan Grace
Jmichael Grace
Craig Mcdonald | 46.74c | - | MS | West Lauderdale | East Mississippi Classic | Thu, Apr 9 |
| 65. | | Relay Team | 46.95a | - | MS | West Lowndes | MHSAA 1A State Championships | Sat, May 9 |
| 66. | | Relay Team | 47.04c | - | MS | New Hope | East Mississippi Classic | Thu, Apr 9 |
| 67. | | Relay Team | 47.20a | - | MS | St Martin | Southern Mississippi HS Invitational | Sat, Mar 7 |
| 68. | | Ju'Wan Brady
Jermey Johnson
Tony Jones
Michael Griffin | 47.26a | - | MS | Greenville/Weston | Southern Mississippi HS Invitational | Sat, Mar 7 |
| 69. | | Relay Team | 47.32a | - | MS | Nanih Waiya | MHSAA 1A State Championships | Sat, May 9 |
| 70. | | J. C. Lockett
Ladarius Brimage
Antonio Edwards
Perry Amos | 47.33a | - | MS | Mendenhall | Southern Mississippi HS Invitational | Sat, Mar 7 |
| 71. | | Ladaren Bates
Zan Carter
Jordan Christian
Jonathan Coleman | 47.34c | - | MS | Louisville | Meridian HS Invitational | Sat, Mar 28 |
| 72. | | Demetric Hambrick
Brian Hancock
Oneal Mccarthy
Shavon Sherrod | 48.14c | - | MS | Neshoba Central | Meridian HS Invitational | Sat, Mar 28 |
| 73. | | Eric Dixen
Deyuntae Durr
Lee Bo
Riccia Durr | 48.77a | - | MS | Magee | Southern Mississippi HS Invitational | Sat, Mar 7 |
| 74. | | Relay Team | 56.53a | - | MS | Wingfield | Southern Mississippi HS Invitational | Sat, Mar 7 |